Leland W K Chung Selected Research

Intercellular Signaling Peptides and Proteins (Growth Factors)

9/2014	RANK-mediated signaling network and cancer metastasis.
7/2006	Met-Independent Hepatocyte Growth Factor-mediated regulation of cell adhesion in human prostate cancer cells.
1/2006	Hypoxia increases VEGF-A production by prostate cancer and bone marrow stromal cells and initiates paracrine activation of bone marrow endothelial cells.
1/2005	Perlecan knockdown in metastatic prostate cancer cells reduces heparin-binding growth factor responses in vitro and tumor growth in vivo.
3/2004	Modulation of prostate cancer growth in bone microenvironments.

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Leland W K Chung Research Topics

Disease

106	Prostatic Neoplasms (Prostate Cancer) 01/2022 - 01/2002
89	Neoplasms (Cancer) 06/2023 - 01/2002
46	Neoplasm Metastasis (Metastasis) 01/2022 - 01/2002
8	Hypoxia (Hypoxemia) 10/2014 - 01/2006
7	Circulating Neoplastic Cells 01/2019 - 03/2011
5	Breast Neoplasms (Breast Cancer) 01/2022 - 04/2013
5	Carcinoma (Carcinomatosis) 01/2013 - 04/2003
4	Renal Cell Carcinoma (Grawitz Tumor) 06/2023 - 12/2006
4	Disease Progression 11/2018 - 04/2011
3	Kidney Neoplasms (Kidney Cancer) 06/2023 - 02/2013
3	Brain Neoplasms (Brain Tumor) 01/2019 - 10/2015
3	Starvation 01/2013 - 05/2007
2	Lung Neoplasms (Lung Cancer) 12/2021 - 02/2015
2	B-Cell Lymphoma (Lymphoma, B Cell) 01/2019 - 07/2007
2	Prostatic Hyperplasia (Benign Prostatic Hyperplasia) 09/2009 - 10/2004
2	Osteosarcoma (Osteogenic Sarcoma) 09/2007 - 01/2002
1	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 12/2021

Drug/Important Bio-Agent (IBA)

38	AndrogensIBA 01/2021 - 01/2002
30	Proteins (Proteins, Gene)FDA Link 01/2020 - 05/2002
17	Androgen Receptors (Androgen Receptor)IBA 01/2019 - 06/2002
12	Coloring Agents (Dyes)IBA 06/2023 - 05/2010
12	Transcription Factors (Transcription Factor)IBA 12/2018 - 01/2002
12	Hormones (Hormone)IBA 01/2016 - 01/2002
11	Biomarkers (Surrogate Marker)IBA 09/2015 - 08/2004
11	Prostate-Specific Antigen (Semenogelase)IBA 11/2011 - 06/2002
9	CarbocyaninesIBA 06/2023 - 02/2013
9	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2019 - 05/2007
8	LigandsIBA 12/2016 - 08/2004
8	AntibodiesIBA 09/2016 - 03/2004
8	OsteocalcinIBA 12/2007 - 01/2002
7	Peptides (Polypeptides)IBA 12/2021 - 05/2010
7	ElementsIBA 03/2016 - 11/2003
7	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 09/2014 - 01/2006
6	AnionsIBA 12/2021 - 05/2010
5	Fluorescent Dyes (Fluorescent Probes)IBA 12/2021 - 01/2008
5	MicroRNAs (MicroRNA)IBA 01/2019 - 11/2008
5	Thymidine KinaseIBA 01/2019 - 02/2003
5	Matrix Metalloproteinases (MMPs)IBA 01/2017 - 03/2004
5	LuciferasesIBA 01/2016 - 01/2002
5	Small Interfering RNA (siRNA)IBA 10/2014 - 09/2006
5	IntegrinsIBA 09/2014 - 03/2004
5	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 09/2014 - 03/2004
5	Cadherins (E-Cadherin)IBA 03/2014 - 12/2006
5	Conditioned Culture MediaIBA 07/2010 - 03/2005
4	Cisplatin (Platino)FDA LinkGeneric 06/2023 - 01/2019
4	Monoamine Oxidase (MAO)IBA 01/2019 - 07/2014
4	Messenger RNA (mRNA)IBA 10/2014 - 10/2005
4	MHI-148IBA 10/2014 - 05/2010
3	Ganciclovir (Cytovene)FDA LinkGeneric 01/2019 - 02/2004
3	ProdrugsIBA 01/2019 - 02/2004
3	OsteonectinIBA 01/2019 - 12/2011
3	Hydrogen Peroxide (Hydroperoxide)FDA LinkGeneric 01/2017 - 10/2006
3	heptamethine cyanine dyeIBA 01/2017 - 05/2010
3	VimentinIBA 09/2016 - 12/2006
3	Liposomes (Liposome)IBA 10/2014 - 10/2005
3	EnzymesIBA 07/2014 - 01/2013
3	AntigensIBA 03/2014 - 01/2007
3	IronIBA 03/2014 - 04/2011
3	IR-783IBA 01/2014 - 05/2010
3	PolymersIBA 06/2013 - 08/2004
3	Tumor Biomarkers (Tumor Markers)IBA 01/2011 - 03/2004
3	Cyclic AMP-Dependent Protein Kinases (cAMP-Dependent Protein Kinase)IBA 12/2006 - 03/2005
3	Cyclic AMP (AMP, Cyclic)IBA 12/2006 - 03/2005
3	Carrier Proteins (Binding Protein)IBA 12/2006 - 03/2005
3	Heparin (Liquaemin)FDA LinkGeneric 07/2006 - 01/2005
2	Keratin-13 (Keratin 13)IBA 01/2022 - 12/2016
2	Cyclin D1IBA 01/2021 - 09/2006
2	Ubiquitin-Protein Ligases (Ubiquitin-Protein Ligase)IBA 12/2018 - 03/2013
2	Interleukin-6 (Interleukin 6)IBA 01/2017 - 09/2009
2	perlecanIBA 03/2016 - 01/2005
2	Docetaxel (Taxotere)FDA Link 12/2015 - 04/2007
2	Receptor Activator of Nuclear Factor-kappa B (TRANCE-R)IBA 09/2014 - 08/2008
2	CateninsIBA 03/2014 - 01/2012
2	Metalloproteases (Metalloproteinases)IBA 01/2013 - 12/2012
2	DisintegrinsIBA 01/2013 - 12/2012
2	Matrix Metalloproteinase 7 (Matrilysin)IBA 01/2013 - 04/2003
2	Integrin alphaVIBA 01/2010 - 10/2005
2	ChemokinesIBA 11/2009 - 09/2009
2	Phosphotransferases (Kinase)IBA 06/2009 - 12/2006
2	Neutralizing AntibodiesIBA 07/2007 - 01/2006
2	Integrin-Binding SialoproteinIBA 09/2006 - 03/2005
2	NF-kappa B (NF-kB)IBA 07/2005 - 04/2004
2	Cholecalciferol (Vitamin D3)FDA Link 03/2005 - 06/2002
2	Acyclovir (Aciclovir)FDA LinkGeneric 03/2004 - 02/2004
1	Cytochromes c (Cytochrome c)IBA 06/2023
1	CaspasesIBA 06/2023
1	gamma Catenin (Plakoglobin)IBA 01/2022
1	Simvastatin (Zocor)FDA LinkGeneric 12/2021
1	CholesterolIBA 12/2021

Therapy/Procedure

27	Therapeutics 06/2023 - 01/2002
14	Castration 01/2022 - 07/2010
8	Quantum Dots (Quantum Dot) 01/2022 - 08/2004
6	Drug Therapy (Chemotherapy) 06/2023 - 03/2004
3	Precision Medicine 01/2021 - 09/2013
3	Subcutaneous Injections 06/2017 - 08/2004
2	Prostatectomy (Retropubic Prostatectomy) 10/2019 - 07/2010
2	Intravenous Administration 01/2016 - 11/2003
2	Injections 04/2013 - 11/2006
2	Radiotherapy 01/2013 - 11/2008
2	Semiconductors 01/2007 - 08/2004